Ongoing projects

E-compared

In 2010, 30 million Europeans were affected by depression and their number is still growing. Half of Europeans in need of mental care for depression do not have access to care services, do not always receive evidence-based treatments, are confronted with long waiting lists or high care expenditures. Internet-based treatment has the potential to addresses the drawbacks of standard care and keep depression treatment of high quality and affordable.

 E-COMPARED will conduct comparative effectiveness research in routine specialized mental care settings on the (cost-) effectiveness of internet-based treatment for depression in comparison with standard care. Health care systems, and -policies, existing ICT infrastructures and their uptake will be taken into account. 

 E-COMPARED aims to

1) Evaluate EU mental health policies/guidelines for standard and internet-based care for depression in specialized care settings in countries with different health care systems and access levels of standard and internet-based care;

2) Compare clinical efficacy and cost-effectiveness of internet-based treatment and treatment as usual within controlled research settings,

3) Carry out pragmatic randomized controlled trials to study how internet-based depression treatment can be effectively implemented within routine specialized care settings,

4) Predict which patient groups could benefit from internet-based treatment vs. standard treatment by modeling patient characteristics;

 5)Develop evidence based recommendations on how internet-based depression treatment can be cost-effectively integrated into routine specialized care systems for depression in EU mental health care systems, and develop a business case to ensure structural implementation of these services.

 E-COMPARED is multidisciplinary (psychology, HTA, ICT, care) and its members have a front runners position in internet-based treatment for common mental health disorders, e.g. through participating in FP7 projects (ICT4Depression, ROAMER)..

Partners:

STICHTING VU-VUMC VUA Netherlands
LINKOPINGS UNIVERSITET LIU Sweden
FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN NURNBERG FAU Germany
LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE LSHTM United Kingdom
STICHTING GGZ INGEEST GGZ INGEEST Netherlands
UNIVERSITAT JAUME I DE CASTELLON UJI Spain
LEUPHANA UNIVERSITAT LUNEBURG ULG Germany
UNIVERSITY OF LIMERICK UL Ireland
UNIVERSITAET BERN UBERN Switzerland
UNIVERSITAT DE VALENCIA UVEG Spain
SZKOLA WYZSZA PSYCHOLOGII SPOLECZNEJ SWPS Poland
INESC PORTO – INSTITUTO DE ENGENHARIA DE SISTEMAS E
COMPUTADORES DO PORTO INESC PORTO Portugal
UNIVERSITE PARIS XII VAL DE MARNE UPEC France
GLOBAL ALLIANCE OF MENTAL ILLNESS ADVOCACY NETWORKS

Objectives

Across Europe, the treatment of depression (with or without chronicity) can be improved both in terms of accessibility and clinical and cost-effectiveness. A number of studies have investigated how depression treatment in primary and specialised care settings can be improved in terms of increased accessibility in the community and more efficient use of limited resources. The effectiveness and efficiency with which resources are being used can be enhanced, by means of improved models of care such as ‘collaborative care’ or ‘disease management’ approaches or ‘stepped care’ initiatives. Blending face-to-face treatment with web-based treatment components is another powerful strategy to increase the cost-effectiveness of adult depression treatment services that can be integrated with the successful models mentioned above. In order to investigate this potential, we will assess the current state of depression treatment policies, practices, and clinical guidelines for the treatment of depression in routine primary and specialised care settings across a subset of eight EU countries. We will then evaluate the clinical and cost-effectiveness of web-based and blended treatments for depression compared to standard face-to-face treatments as currently delivered in usual care across these settings.

Specific objectives
– To consult and discuss the current state of the art of depression treatment with national and European stakeholders, including representatives of patient organisations for depression.
– To assess patients’ needs and preferences for Internet-based treatments for depression
– To present and consult on the objectives of E-COMPARED with these stakeholders.
– To explore what is known about current advantages, disadvantages and harm on Internet-based treatments compared to TAU and how these may be overcome.
– To investigate what the reasons are for participating countries to invest in blended Internet-based treatments for depression in primary and specialised mental care services formats from the perspective of relevant stakeholders.
– To explore the future plans on Internet-based treatments across a number of European networks such as the FP7 ROAMER project and the European Alliance Against Depression.

WP 1Adult depression treatment in primary care and routine specialised mental care services
WP 2 Comparing the clinical and cost-effectiveness of Internet- based treatment and treatment as usual
WP 3 Economic Modelling Studies
WP 4 Personalised Depression Treatment Modelling
WP 5 Synthesis of results and EU recommendations
WP 6 Dissemination and business case development
WP 7 Project management

GAMIAN is an active partner in WP 6:

Development and maintenance of the dissemination plan (M1-36). To ensure that maximum value will be created from the E-COMPARED project and to allow optimal dissemination, a Dissemination plan will be generated. This plan will be updated each year. The Dissemination plan will detail how the E-COMPARED project will disseminate project results to all stakeholders. Moreover, it will describe the target audiences, key messages, methods and frequency of dissemination as well as the responsibilities of the consortium members with respect to dissemination (see also B.3.2.1b). The development and updates of the plan will be led by dr. Thomas Berger (UBERN) in collaboration with the project partners, and will need approval from the Executive Committee. The plan will be finished at month 6 and will be updated at the end of each year.  

Development of a business case. WP1-5 will generate a wealth of knowledge on mental health policies, treatment regimens, cost-effectiveness, economic impact of Internet-based blended depression treatment in routine practice and in its train recommendations for the treatment of other mental disorders such as anxiety, alcohol dependence, and differences in implementation of Internet-based treatments and stakeholders perspectives. On the basis of this knowledge, a business case will be developed for the implementation of Internet-based depression treatment within Europe based on different levels of Internet-based treatment implementation (WP2-WP4), allowing for the state of the art eMental health facilities and levels of implementation while taking into account variations between countries. Business opportunities will be an integral part of the business case.  

Development and maintenance of the E-COMPARED website (UBERN; M1- 36 A project website consisting of two parts will be developed. The ‘secure part’ will have functionalities for document exchange, consortium and WP-specific email lists, web-based conferencing, calendar functions, methods portal and data exchange. The ‘open access’ part will be used for communication with stakeholders, including policy makers, health professionals, researchers, educational platforms, patients and the general public. The website will be live after 3 months

 
Execution of the Dissemination plan. Dissemination activities for all stakeholders, as formulated in the Dissemination plan, will be executed. These include the development and dissemination of project information on the project website, in brochures, newsletters, press releases, publications in peer reviewed scientific journals and policy journals, and oral and poster presentations at conferences and workshops. All project partners will be encouraged to attend major meetings and conferences, and where possible create opportunities to promote E-COMPARED at such events, e.g. as invited speaker. Partners will also be encouraged to actively use their stakeholder networks for the purpose of further dissemination. Further, we will collaborate with Mental Health Europe and the European Depression Association (EDA) to ensure widespread distribution of the results. During the project Consortium partners will report on the progress of E-COMPARED at national and international conferences and health policy (summit) meetings as well as in scientific and professional journals (representing the different disciplines involved in E-COMPARED). A final international conference (M36, CH) will be organized for a broad group of stakeholders (e.g. policy makers such as politician and administrators, mental health care professionals, patients, patient organizations, scientists and the general public) at which the key outcomes of the project will be presented through presentations and workshops. Issues to be discussed will include the opportunities and potential bottlenecks in terms of health profits, requirements, health policy, costs, feasibility, organizational issues and technologies. The final meeting will be broadly advertised.