Psych-STRATA is a research project funded by the European Commission that focuses on personalised mental health treatment.

The project tackles treatment resistance (TR), a problem affecting a third of patients with major mental disorders who don’t respond to drug therapy. These patients often face a trial-and-error treatment approach, which is inefficient and stressful.

The main aim is to address this by identifying at-risk individuals earlier, developing personalised treatment strategies grounded in the biological basis of TR, and efficiently implementing these insights in clinical practice and treatment guidelines.

Psych-STRATA will examine diverse data, including genetic, biological, digital mental health, and clinical information to better understand TR and identify those at risk. Using Europe-wide clinical trial information, the project will determine optimal treatment strategies for those at risk of TR.

The research will aid in the creation of new machine-learning models to predict TR risk and treatment response. Finally, the project aims to integrate these findings into clinical practice, assisting clinicians and patients in making informed treatment decisions.

Learn more about the project here.